General description
Pre-loaded resin for synthesis of peptide acids containing a C-terminal serine amino-acid residue by Fmoc SPPS. Prepared from a low load Wang resin, to help facilitate the synthesis of longer peptides.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Application
Applications of Fmoc-Ser(tBu)-Wang resin LL (100-200 mesh) include:
In the preparation of a peptide thioester intermediate for use in the solid-phase synthesis of peptide and glycopeptide thioesters using a side-chain-anchoring strategy.[1]
As a solid support in the synthesis of a peptide substrate for use in a reaction to prepare disubstituted pyrazino-oxazine derivatives.[2]
In the synthesis of a peptide intermediate for use in the solid-phase synthesis of tetramic acid derivatives, which have potential applications as pharmaceuticals.[3]

Linkage
Replaces: 04-12-2086

Legal Information
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